Data-dependent early completion of dose-finding trials for drug-combination.

Published in: Statistical methods in medical research (2023)

The performance of the proposed early completion methods was similar to that of the non-early completion methods. Furthermore, the number of patients for determining early completion before the trial starts was determined and a program code for calculating the dose retainment probability was proposed.

Keyphrases

end stage renal disease
clinical trial
ejection fraction
newly diagnosed
emergency department
study protocol
quality improvement
peritoneal dialysis
phase iii
data analysis