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Effect of Ocrelizumab on B- and T-Cell Receptor Repertoire Diversity in Patients With Relapsing Multiple Sclerosis From the Randomized Phase III OPERA Trial.

Sarah A LaurentNicolas B StrauliErica L EggersHao WuBrady MichelStanislas DemuthArumugam PalanichamyMichael R WilsonMarina SirotaRyan D HernandezBruce Anthony Campbell CreeAnn E HermanH-Christian von Büdingen
Published in: Neurology(R) neuroimmunology & neuroinflammation (2023)
This is a substudy (BE29353) of the OPERA I (WA21092; NCT01247324) trial. Date of registration, November 23, 2010; first patient enrollment, August 31, 2011.
Keyphrases
  • phase iii
  • multiple sclerosis
  • open label
  • clinical trial
  • double blind
  • phase ii
  • placebo controlled
  • white matter
  • case report
  • health insurance
  • systemic lupus erythematosus
  • disease activity
  • affordable care act