Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.
Wataru TakakiHirotaka KonishiDaiki MatsubaraKatsutoshi ShodaTomohiro AritaSatoshi KataokaJun ShibamotoHirotaka FurukeKazuya TakabatakeHiroki ShimizuShuhei KomatsuAtsushi ShiozakiTakeshi KubotaKazuma OkamotoEigo OtsujiPublished in: International journal of molecular sciences (2022)
Plasma HMGB1 concentrations are a prognostic marker in GC patients. Extracellular HMGB1 promotes cancer progression and has potential as a novel treatment target in GC cells for rTM.
Keyphrases
- end stage renal disease
- induced apoptosis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- papillary thyroid
- transcription factor
- prognostic factors
- cell cycle arrest
- squamous cell carcinoma
- cell death
- patient reported outcomes
- endoplasmic reticulum stress
- squamous cell
- combination therapy
- replacement therapy