Tubular dentin formation by TGF-β/BMP signaling in dental epithelial cells.

Yoon Seon LeeYeoung-Hyun ParkYou-Mi SeoHye-Kyung LeeJoo Cheol Park

Published in: Oral diseases (2022)

Taken together, Smad4-dependent TGF-β1/BMP2 signaling regulates Cpne7 in dental epithelial cells, and CPNE7 protein secreted from pre-ameloblasts mediates odontoblast differentiation via epithelial-mesenchymal interaction.

Keyphrases

transforming growth factor
mesenchymal stem cells
oral health
epithelial mesenchymal transition
bone marrow
stem cells
bone regeneration
protein protein
endothelial cells
binding protein
small molecule