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Pharmacokinetic study of erlotinib in a pregnant woman with advanced non-small cell lung cancer and observation of the effects on the child growth.

Yuka AidaMasahiro OhgamiYuji MukaiMasashi MatsuyamaMana Obata-YasuokaToyomi SatohMasato HommaIkuo SekineNobuyuki Hizawa
Published in: British journal of clinical pharmacology (2024)
Erlotinib use during the second and third trimester of pregnancy did not seem to cause any untoward effects on the developing foetus, or any long-lasting effects that could be detected during 6 years of follow-up of the child.
Keyphrases
  • advanced non small cell lung cancer
  • epidermal growth factor receptor
  • preterm birth
  • mental health
  • pregnancy outcomes
  • pregnant women
  • tyrosine kinase
  • case report