Hepatitis B virus reactivation in cancer patients with positive Hepatitis B surface antigen undergoing PD-1 inhibition.

Xuanye ZhangYixin ZhouChen ChenWenfeng FangXiuyu CaiXiaoshi ZhangMing ZhaoBei ZhangWenqi JiangZuan LinYuxiang MaYunpeng YangYan HuangHongyun ZhaoRuihua XuShaodong HongLi Zhang

Published in: Journal for immunotherapy of cancer (2019)

HBV reactivation occurs in a subset of HBsAg-positive cancer patients undergoing anti-PD-1 or anti-PD-L1 immunotherapy. Regular monitoring of HBV DNA and antiviral prophylaxis are advised to prevent this potentially fatal complication.

Keyphrases

hepatitis b virus
patients undergoing
liver failure
papillary thyroid
circulating tumor
squamous cell
cell free
single molecule
young adults
childhood cancer