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Mucormycosis in Children With Hematologic Malignancies: A Case Series and Review of the Literature.

Yvette G T LoeffenFenna ScharlooBianca Frederika GoemansKatja M J Heitink-PolleCaroline A LindemansJan-Tom van der BruggenFerry HagenTom F W Wolfs
Published in: The Pediatric infectious disease journal (2022)
Although survival of mucormycosis improved significantly overtime, it plateaued in the past decades. This series shows that with screening, early diagnostics and early antifungal and if possible surgical treatment, mortality is low and even disseminated disease is salvageable if approached aggressively with a combination of surgery and antifungal treatment. Further research focused on diagnostics, combination antifungal and adjunctive therapy is necessary to enhance the survival of mucormycosis in children.
Keyphrases
  • candida albicans
  • young adults
  • minimally invasive
  • cardiovascular events
  • free survival
  • risk factors
  • stem cells
  • coronary artery disease
  • acute coronary syndrome
  • combination therapy
  • replacement therapy