CD14 down-modulation as a real-time biomarker in Kawasaki disease.
Yutaro InadaMotoshi SonodaYumi MizunoKenichiro YamamuraYoshitomo MotomuraAoba TakumaKenji MurataKenji FurunoJunichiro TezukaYasunari SakaiShouichi OhgaJunji KishimotoKoki HosakaSatomi SakataToshiro HaraPublished in: Clinical & translational immunology (2023)
Monitoring CD14 down-modulation on monocytes in real-time is a valuable strategy for assessing treatment response, distinguishing KD relapse from concomitant infections and selecting second-line therapy after IVIG treatment in KD patients. The interplay between inflammation and oxidative stress likely plays a crucial role in the development of KD.