Intestinal mucus affinity and biological activity of an orally administered antibacterial and anti-inflammatory peptide.

Aline DupontYani KaconisInes YangThorben AlbersSabrina WoltemateLena HeinbockelMats AnderssonSebastian SuerbaumKlaus BrandenburgMathias W Hornef

Published in: Gut (2014)

Our findings demonstrate the anti-inflammatory activity and mucus affinity of the synthetic AMP Pep19-2.5 and characterise the influence on microbiota composition and enteropathogen infection after oral administration.

Keyphrases

anti inflammatory
protein kinase
capillary electrophoresis
silver nanoparticles
mass spectrometry