Highly Sensitive Squaraine-Based Water-Soluble Far-Red/Near-Infrared Chromofluorogenic Thiophenol Probe.
Li XiongJun MaYan HuangZihe WangZhiyun LuPublished in: ACS sensors (2017)
A squaraine-based far-red/near-infrared fluorescent probe (SQ-DNBS) was exploited for thiophenol detection. SQ-DNBS is a colorimetric and "off-on" fluorometric dual-channel "naked-eye" chemosensor showing high selectivity, high sensitivity (detection limit: 9.9 nM), and rapid response to thiophenol in aqueous solution. SQ-DNBS also can be used in practical applications for the detection of thiophenol in water samples. Photophysical and spectral characterization results revealed that the probing mechanism of SQ-DNBS toward thiophenol lies in the thiolate-mediated cleavage reaction. Our discovery demonstrates the potential of the arylmethylene-squaraine skeleton as a promising fluorophore unit to construct high-performance far-red/near-infrared chemosensors.
Keyphrases
- fluorescent probe
- living cells
- loop mediated isothermal amplification
- aqueous solution
- label free
- water soluble
- real time pcr
- gold nanoparticles
- sensitive detection
- small molecule
- single molecule
- optical coherence tomography
- single cell
- quantum dots
- climate change
- magnetic resonance
- risk assessment
- nitric oxide
- mass spectrometry
- human health