Dual-Ligand-Modified Liposomes Co-Loaded with Anti-Angiogenic and Chemotherapeutic Drugs for Inhibiting Tumor Angiogenesis and Metastasis.

Fangqing WangYanying LiHong JiangChenglei LiZhaohuan LiCuiping QiZhi-Peng LiZhiqin GaoBo ZhangJing-Liang Wu

Published in: International journal of nanomedicine (2021)

CUCA/GA&Gal-Lip hold great potentials in hepatoma-targeting delivery of antitumor drugs and can achieve anti-angiogenic and anti-metastatic effects by simultaneously blocking VEGF/VEGFR2 signal pathway, therefore exhibiting superior anti-hepatoma efficacy.

Keyphrases

vascular endothelial growth factor
drug delivery
small cell lung cancer
squamous cell carcinoma
cancer therapy
signaling pathway
drug induced