Allergic disease in 8-year-old children is preceded by delayed B cell maturation.
A StrömbeckI NordströmK AnderssonH AnderssonS JohansenC MaglioH RabeI AdlerberthA E WoldB HesselmarA RudinAnna-Carin LundellPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
High proportions of neonatal naïve B cells remained as a risk factor for allergic disease in school-aged children. Thus, the accelerated B cell maturation observed among farmers' children may be crucial for the allergy-protective effect of a farming environment.