Systematic review with meta-analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis controlled trials.

A CholapraneeG S HazlewoodG G KaplanL Peyrin-BirouletAshwin N Ananthakrishnan

Published in: Alimentary pharmacology & therapeutics (2017)

Anti-TNF and anti-integrin biological agents are effective in inducing mucosal healing in UC, with adalimumab being inferior to infliximab or combination therapy. Infliximab and adalimumab were similar in CD.

Keyphrases

ulcerative colitis
combination therapy
rheumatoid arthritis
nk cells
cell migration