Select black men are potential candidates for prostate hemi-ablation based on radical prostatectomy histopathology for intermediate-risk prostate cancer-a multicenter SEARCH cohort study.
Sriram DeivasigamaniEric S AdamsShannon StockSrinath KotamartiDenis SéguierTarek TahaLauren E HowardAlireza AminsharifiGhalib JibaraChristopher L AmlingWilliam J AronsonMatthew R CooperbergChristopher J KaneMartha K TerrisZachary KlaassenLourdes Guerrios-RiveraStephen J FreedlandThomas J PolascikPublished in: Prostate cancer and prostatic diseases (2024)
In men with IR-PCa undergoing RP, AA men demonstrated an overall higher likelihood of ≥pT2c with lower upstaging beyond pT2, lower likelihood of EPE and no significant difference in likelihood of SVI and LNI compared to non-AA men. These findings support select AA men to be potential candidates for PGA, such as HA. Clinical factors are predictive of higher pathological stage and adverse pathological outcomes at RP and could be considered when selecting candidates for PGA.