Limbic progesterone receptor activity enhances neuronal excitability and seizures.

Shinnosuke ShionoHuayu SunTamal BatabyalAleksandra LabuzJohn WilliamsonJaideep Kapur Suchitra Joshi

Published in: Epilepsia (2021)

Activation of PRs expressed in the EC and hippocampus increased neuronal excitability and worsened seizures. These receptors may play a role in catamenial epilepsy.

Keyphrases

cerebral ischemia
transcranial direct current stimulation
temporal lobe epilepsy
subarachnoid hemorrhage
blood brain barrier
brain injury
estrogen receptor
cognitive impairment
binding protein