Club cell protein (CC)16 as potential lung injury marker in a porcine 72 h polytrauma model.
Johannes GrevenJan Tilmann VollrathFelix BläsiusZhizhen HeEftychios BolierakisKlemens HorstPhilipp StörmannAleksander J NowakMarija SimicIngo MarziFrank HildebrandBorna ReljaPublished in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2022)
The data confirm for the first time in a larger animal polytrauma model that lung damage was indicated by systemic and/or local CC16 response. Thus, early plasma and late BAL CC16 levels might be suitable to be used as markers of lung injury in this polytrauma model.