Rapid On-site Molecular Evaluation in thyroid cytopathology: A same-day cytological and molecular diagnosis.

Caterina De LucaRoberta SgarigliaMariantonia NacchioPasquale PisapiaIlaria MigliaticoEduardo CleryGianluca GragnanoSevero CampioneElena VigliarUmberto MalapelleGianfranco De DominicisClaudio BellevicineGiancarlo Troncone

Published in: Diagnostic cytopathology (2020)

The FNA needle rinse can be directly genotyped. This obviates the need of cell block preparation, making possible a rapid combined morphological and molecular evaluation. Since DNA extraction is no longer necessary, the cytopathologist can perform ROME him/herself.

Keyphrases

single molecule
single cell
cell free
stem cells
circulating tumor
mass spectrometry
mesenchymal stem cells
bone marrow
liquid chromatography
clinical evaluation