Single-Cell RNA Sequencing Identifies Crucial Genes Influencing the Polarization of Tumor-Associated Macrophages in Liver Cancer.

Kedong XuMingyi DongZhengqiang WuLinfei LuoFei XieFan LiHongyan HuangFenfen WangXiaofeng XiongZhili Wen

Published in: International journal of genomics (2024)

Our findings suggest the PRDM1 gene is a key regulator of M2 macrophage polarization, contributing to the immunosuppressive TME in HCC.