Exploring Sex Differences of Beta-Blockers in the Treatment of Hypertension: A Systematic Review and Meta-Analysis.
Nick WilmesEveline M van LuikEsmée W P VaesMaud A M VesseurSophie A J S LavenZenab Mohseni-AlsalhiDaniek A M MeijsCédric J R DikovecSander de HaasMarc E A SpaandermanChahinda Ghossein-DohaPublished in: Biomedicines (2023)
BBs comparably lowered BP and HR in both sexes. The lack of change in CO in males suggests that the reduction in BP is primarily due to a decrease in vascular resistance. Furthermore, females were underrepresented compared to males. We recommend that future research should include more females and sex-stratified data when researching the treatment effects of antihypertensives.