Professional antigen-presenting Tbet + CD11c + B cells correlate with bone destruction in untreated rheumatoid arthritis.

Sarah McGrathKristoffer GrimstadKatrin ThorarinsdottirKristina ForslindDaniel GlinatsiMonica Leu AgeliiAlaitz AranburuTimothy SundellCharlotte A JonssonAlessandro CamponeschiAnna-Karin Hultgård EkwallAndreas TilevikInger Gjertsson Inga-Lill Mårtensson

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

MBCs contribute to the pathogenesis of RA by promoting bone destruction through antigen presentation, T-cell activation and Th17 polarisation.

Keyphrases

rheumatoid arthritis
bone mineral density
disease activity
soft tissue
case report
bone loss
bone regeneration
ankylosing spondylitis
interstitial lung disease
postmenopausal women
body composition
systemic lupus erythematosus