Subclinical signs of podocyte injury associated with Circulating Anodic Antigen (CAA) in Schistosoma mansoni-infected patients in Brazil.

Mariana Silva Sousa Gdayllon Cavalcante Meneses Govert Jan van Dam Paul Leo Albert Maria Corstjens Rosangela Lima de Freitas Galvão Marta Cristhiany Cunha Pinheiro Alice Maria Costa Martins Elizabeth de Francesco Daher Fernando Schemelzer de Moares Bezerra

Published in: Revista da Sociedade Brasileira de Medicina Tropical (2023)

S. mansoni-infected individuals presented subclinical signs of glomerular damage that may reflect podocyte injury. However, no causal effect on long-term renal function was observed after PZQ treatment.

Keyphrases

diabetic nephropathy
high glucose
oxidative stress
endothelial cells
combination therapy