Reflecting the human lip in vitro: Cleft lip skin and mucosa keratinocytes keep their identities.
Silvia RihsLudovica ParisiAnic LauenerFarah MansourIsabelle SchnyderGabriela M DekanyGiorgio C La ScalaChristos KatsarosMartin DegenPublished in: Oral diseases (2024)
Our findings promote patient-derived cells retaining their original identities as astonishing and clinically relevant in vitro tools. Such cells allow a better molecular understanding of various lip-associated pathologies as well as their modeling in vitro, including but not restricted to orofacial clefts.