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Reflecting the human lip in vitro: Cleft lip skin and mucosa keratinocytes keep their identities.

Silvia RihsLudovica ParisiAnic LauenerFarah MansourIsabelle SchnyderGabriela M DekanyGiorgio C La ScalaChristos KatsarosMartin Degen
Published in: Oral diseases (2024)
Our findings promote patient-derived cells retaining their original identities as astonishing and clinically relevant in vitro tools. Such cells allow a better molecular understanding of various lip-associated pathologies as well as their modeling in vitro, including but not restricted to orofacial clefts.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endothelial cells
  • endoplasmic reticulum stress
  • signaling pathway
  • wound healing
  • single molecule
  • pi k akt
  • induced pluripotent stem cells