Distress response in granulosa cells of women affected by PCOS with or without insulin resistance.
Mauro CozzolinoSonia HerraizYigit CakirogluJuan Antonio Garcia-VelascoBulent TirasAlberto PachecoSusana RabadanGraciela KohlsAna Isabel BarrioAntonio PellicerEmre SeliPublished in: Endocrine (2022)
genes. Our study contributes to the understanding of the molecular mechanisms underlying the pathological changes that occur in the follicular microenvironment of women with PCOS.
Keyphrases
- polycystic ovary syndrome
- insulin resistance
- induced apoptosis
- adipose tissue
- metabolic syndrome
- high fat diet
- skeletal muscle
- stem cells
- type diabetes
- high fat diet induced
- genome wide
- gene expression
- cell proliferation
- transcription factor
- dna methylation
- glycemic control
- genome wide identification
- genome wide analysis