Intergenerational concordance of brain structure between depressed mothers and their never-depressed daughters.
Fusaka MinamiJinichi HiranoRyo UedaAkihiro TakamiyaMika YamagishiKei KamiyaMasaru MimuraBun YamagataPublished in: Psychiatry and clinical neurosciences (2022)
The current study provides biological evidence for greater vulnerability of daughters, but not sons, in developing depression whose mothers have a history of depression. Our findings extend our knowledge on the pathophysiology of major psychiatric conditions that show sex biases and may contribute to the development of novel interventions targeting high-risk individuals.