Mesenchymal Stem Cell Exosomes Promote Growth Plate Repair and Reduce Limb-Length Discrepancy in Young Rats.
Keng Lin WongShipin ZhangSharon Si Heng TanYi Ann CheowRuenn Chai LaiSai Kiang LimJames Hoi Po HuiWei Seong TohPublished in: The Journal of bone and joint surgery. American volume (2022)
This proof-of-concept study demonstrates for the first time the potential use of MSC exosomes as a minimally invasive cell-free therapeutic to promote physeal repair and reduce limb-length discrepancy following growth plate injuries.