Development of a highly sensitive method for detection of FLT3D835Y.

Yao GuoHonghua SunDengyang ZhangYuming ZhaoMingxia ShiMing YangShu XingXueqi FuTing BinBo LuShunjie WuXiaojun XuXuesong XuYun ChenZhizhuang Joe Zhao

Published in: Biomarker research (2020)

We have developed a simple and highly sensitive method that will allow for detection of FLT3D835Y at a very low level. This method may have major clinical implications for treatment of AML.

Keyphrases

acute myeloid leukemia
label free
tyrosine kinase
loop mediated isothermal amplification
fluorescent probe
molecularly imprinted
mass spectrometry
acute lymphoblastic leukemia
replacement therapy
single molecule
solid phase extraction