Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure.

Rafaëla SchoberBianca BrandusThessa LaeremansGilles IserentantCamille RolinGéraldine DessillyJacques ZimmerMichel MoutschenJoeri L AertsXavier DervillezCarole Seguin-Devaux

Published in: Journal of translational medicine (2023)

NK cell-mediated killing of HIV-1 infected cells by NaMiX represents a promising approach to support HIV-1 cure strategies.

Keyphrases

hiv infected
antiretroviral therapy
natural killer cells
hiv positive
human immunodeficiency virus
nk cells
induced apoptosis
hiv aids
hiv testing
signaling pathway
hepatitis c virus
cell cycle arrest
men who have sex with men
oxidative stress
endoplasmic reticulum stress
cell proliferation
cell death
pi k akt