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NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation.

Sara BremerNils T VetheMorten SkaubyMargrete KasboElisabet D JohanssonKarsten MidtvedtStein Bergan
Published in: British journal of clinical pharmacology (2017)
The findings of our study support the potential of NFAT-regulated gene expression measurements as a pharmacodynamic tool for additional monitoring of Tac therapy, especially in the context of overimmunosuppression and viraemia.
Keyphrases
  • gene expression
  • dna methylation
  • transcription factor
  • nuclear factor
  • bone marrow
  • mesenchymal stem cells
  • risk assessment
  • toll like receptor
  • cell therapy
  • climate change