Diet-Induced Paternal Obesity Impairs Cognitive Function in Offspring by Mediating Epigenetic Modifications in Spermatozoa.

Yin ZhouHong ZhuHai-Yan WuLu-Yang JinBin ChenHai-Yan PangZhen-Hua MingYi ChengCheng-Liang ZhouMeng-Xi GuoYi-Ting HuangDan-Qing YuJian-Zhong ShengHe-Feng Huang

Published in: Obesity (Silver Spring, Md.) (2019)

The findings provide evidence of intergenerational effects of paternal obesity on cognitive function in offspring occurring via epigenetic spermatozoan modifications.

Keyphrases

insulin resistance
high fat diet
metabolic syndrome
weight loss
dna methylation
high fat diet induced
type diabetes
gene expression
weight gain
adipose tissue
body mass index
physical activity