From Early Radiographic Knee Osteoarthritis to Joint Arthroplasty: Determinants of Structural Progression and Symptoms.
Frank W RoemerC Kent KwohTomoko FujiiMichael J HannonRobert M BoudreauDavid John HunterFelix EcksteinMarkus R JohnAli GuermaziPublished in: Arthritis care & research (2019)
More than half of the knees with no/mild radiographic OA before knee replacement progressed to severe radiographic OA during 4 years of follow-up. BMLs in the patellofemoral joint were more often seen among knees that had no/mild radiographic OA. Worsening pain status may contribute to knee replacement in knees with no/mild radiographic OA.