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Lynch-like syndrome with germline WRN mutation in Bulgarian patient with synchronous endometrial and ovarian cancer.

Zornitsa Bogomilova KamburovaPolina Damyanova DimitrovaDiana Strateva DimitrovaKatya Stefanova KovachevaSavelina Lubenova PopovskaSlavena Enkova Nikolova
Published in: Hereditary cancer in clinical practice (2023)
The presented case contributes to the etiology of LLS and confirms the need for specific genetic testing, together with genetic counseling, in hereditary cancer syndromes. The use of combined information from clinicians, pathologists, genetic counselors, and data from NGS testing for cancer predisposition, clinical surveillance, and follow-up management in women with gynecology cancers, especially SEOC, could be improved.
Keyphrases
  • papillary thyroid
  • squamous cell
  • case report
  • genome wide
  • public health
  • lymph node metastasis
  • electronic health record
  • dna methylation
  • oxidative stress
  • young adults
  • men who have sex with men