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Low-Cost Genetic and Clinical Predictors of Response and Toxicity of Platinum-Based Chemotherapy in Advanced Non-Small Cell Lung Cancer.

Jelena SpasićMilena ČavićNemanja StanicBojan ZaricTomi KovacevicDavorin RadosavljevicLjudmila Nagorni-Obradovic
Published in: Dose-response : a publication of International Hormesis Society (2022)
A set of easily determined genetic and clinical predictors of survival and specific toxicity profiles of platinum-based chemotherapy in advanced lung adenocarcinoma were determined in this study, which might be useful for the construction of population-specific, time- and cost-efficient prognostic and predictive algorithms.
Keyphrases
  • advanced non small cell lung cancer
  • low cost
  • oxidative stress
  • genome wide
  • epidermal growth factor receptor
  • machine learning
  • locally advanced
  • deep learning
  • squamous cell carcinoma
  • dna methylation
  • tyrosine kinase