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Selective Inhibition of β-Catenin/Co-Activator Cyclic AMP Response Element-Binding Protein-Dependent Signaling Prevents the Emergence of Hapten-Induced Atopic Dermatitis-Like Dermatitis.

Haruna Matsuda-HiroseTomoko YamateMizuki GotoAkira KatohHiroyuki KoujiYuya YamamotoTakashi SakaiNaoto UemuraTakashi KobayashiYutaka Hatano
Published in: Annals of dermatology (2019)
These results suggest that β-catenin/CBP-dependent signaling might be involved in the pathogenesis of AD and could be a therapeutic target.
Keyphrases
  • atopic dermatitis
  • binding protein
  • epithelial mesenchymal transition
  • cell proliferation
  • high glucose
  • diabetic rats
  • protein kinase
  • mouse model
  • endothelial cells
  • signaling pathway