Evaluation of CD44s, CD44v6, CXCR2, CXCL1, and IL-1β in Benign and Malignant Tumors of Salivary Glands.

Fonthip LaohavisudhiTitikorn ChunchaiNatnicha KetchaikosolWacharaporn ThosapornNipon ChattipakornSiripron C Chattipakorn

Published in: Diagnostics (Basel, Switzerland) (2022)

CD44s, CD44v6, CXCR2, and IL-1β expressions were found to be higher in salivary gland tumors. However, IL-1β alone may play a crucial role in the aggressiveness of salivary gland tumors as this cytokine was expressed only in the malignant group with high expression associated with high-grade malignancy.

Keyphrases

high grade
nk cells
low grade
cell migration
binding protein