CD44v6 chimeric antigen receptor T cell specificity towards AML with FLT3 or DNMT3A mutations.

Ling TangHongming HuangYutong TangQing LiJue WangDengju LiZhaodong ZhongPing ZouYong YouYang CaoYingjie KongAnyuan GuoShu ZhouHuimin LiFankai MengYi XiaoXiaojian Zhu

Published in: Clinical and translational medicine (2022)

Collectively, CD44v6 is a promising target of CAR-T for AML patients with FLT3 or DNMT3A mutations.

Keyphrases

acute myeloid leukemia
dna methylation
allogeneic hematopoietic stem cell transplantation
tyrosine kinase
nk cells
acute lymphoblastic leukemia