Genetic characterization of KCNQ1 variants improves risk stratification in type 1 long QT syndrome patients.

Charles Morgat Véronique Fressart Alessandra Pia PorrettaNathalie NeyroudAnne MessaliYassine TemmarVincent Algalarrondo Elodie SurgetAdrien BlochAntoine Leenhardt Isabelle Denjoy Fabrice Extramiana

Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)

Heterozygous carriers of JLNS variants have a lower risk of cardiac arrhythmic events than other LQT1 patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
copy number
left ventricular
gene expression
heart failure
dna methylation
case report