Effects of letrozole alone or in combination with gonadotropins on ovulation induction and clinical pregnancy in women with polycystic ovarian syndrome: a systematic review and meta-analysis of randomized controlled trials.

Saeed BaradwanFaisal Al-ShalhoubMajed Saeed AlshahraniSamah HimaydaRayan AlSghanHussein SabbanInass Hassan AhmadMarwa Fekry Mohamed El SayedEntesar Omar MohamadAbdulhadi A AlAmodiAhmed Mohamed AbdelhakimKareem Shaheen

Published in: Hormones (Athens, Greece) (2024)

Letrozole in combination with gonadotropin is superior to letrozole alone in improving ovulation induction and clinical pregnancy among PCOS patients. More trials are required to confirm our findings.

Keyphrases

polycystic ovary syndrome
insulin resistance
end stage renal disease
ejection fraction
preterm birth
newly diagnosed
chronic kidney disease
early breast cancer
prognostic factors
pregnancy outcomes
metabolic syndrome
type diabetes
case report