The Prognostic Role of MYC Structural Variants Identified by NGS and FISH in Multiple Myeloma.
Neeraj SharmaJames B SmadbeckNadine H AbdallahCinthya Zepeda-MendozaMoritz BinderKathryn E PearceYan W AsmannJess F PetersonRhett P KetterlingPatricia T GreippPeter Leif BergsagelS Vincent RajkumarShaji K KumarLinda B BaughnPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Understanding the impact of different MYC SVs on disease outcome is necessary for the reliable interpretation of MYC SVs in multiple myeloma. NGS approaches should be considered as a replacement technique for a more comprehensive evaluation of the multiple myeloma clone.