The Prevalence and Risk Factors of Acute Kidney Injury during Colistin Therapy: A Retrospective Cohort Study from Lebanon.

Rima Moghnieh Rola Husni Mariana HelouDania AbdallahLoubna SinnoMarwa JadayelKawsar DiabCarmen ChamiMarah Al RachidDiana Caroline AwadAline ZaiterMohamed H Sayegh

Published in: Antibiotics (Basel, Switzerland) (2023)

The findings of this study suggest that old age, history of chronic kidney disease, and concomitant vasopressor treatment are all independent predictors of CMS-induced AKI. The risk of developing severe AKI significantly increases with CMS DOT. Understanding the risk factors of nephrotoxicity is essential for improving prognosis and treatment outcomes.

Keyphrases

acute kidney injury
chronic kidney disease
cardiac surgery
risk factors
drug induced
escherichia coli
end stage renal disease
pseudomonas aeruginosa
high glucose
diabetic rats
drug resistant
multidrug resistant
early onset
klebsiella pneumoniae
acinetobacter baumannii
oxidative stress
cystic fibrosis