Relapse rates after withdrawal of thiopurines in patients with inflammatory bowel disease.

Mukesh Kumar Ranjan Sudheer Kumar Vuyyuru Bhaskar Kante Peeyush Kumar Sandeep K Mundhra Rithvik Golla Raju Sharma Carlos Monteiro Prasenjit Das Govind Kumar Makharia Saurabh Kedia Vineet Ahuja

Published in: International journal of colorectal disease (2022)

Approximately 50% patients with IBD in remission would relapse after 5 years of thiopurine withdrawal. Male sex and shorter treatment duration predict relapse. Treatment should be continued in patients who tolerate and maintain remission on long-term thiopurine.

Keyphrases

patients with inflammatory bowel disease
free survival
ulcerative colitis
disease activity
combination therapy