Corticotropin releasing factor alters the functional diversity of accumbal cholinergic interneurons.

ChIs within the dorsal and ventral striatum can exert a huge influence on network output and motivated behaviors. However, the firing patterns and neuromodulation of ChIs within the ventral striatum,specifically the NAc shell, are understudied. Here we report that NAc shell ChIs have a heterogenous distribution of ChI firing patterns that are labile and can be modulated by the stress-linked neuropeptide CRF and by estrous cycle.