A Case of Magnusiomyces capitatus Peritonitis Without Underlying Malignancies.
Carlos D'AssumpcaoBenson LeeArash HeidariPublished in: Journal of investigative medicine high impact case reports (2018)
Magnusiomyces capitatus is a rare cause of fungal infection in immunocompromised patients, mainly seen in hematological malignancies. M capitatus infections are extremely rare in immunocompetent patients, as it is part of normal human microbial flora. We are presenting an extremely rare case of M capitatus peritonitis in an otherwise immunocompetent patient who suffered from gastrointestinal leakage due to pancreatitis. Fungal identification was performed at reference laboratory by phenotypic characteristics and DNA sequencing of target internal transcribed spacer region of the rRNA gene and the D1-D2 domain of the large-subunit rRNA gene and susceptibility testing by Clinical and Laboratory Standards Institute guidelines (document M27-S4) broth dilution method. He was successfully treated with a combination of surgical repair and voriconazole single therapy.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- rare case
- endothelial cells
- copy number
- microbial community
- single cell
- dna methylation
- liquid chromatography tandem mass spectrometry
- mass spectrometry
- single molecule
- extracorporeal membrane oxygenation
- bone marrow
- simultaneous determination
- cell wall
- liquid chromatography