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Review of electrochemical and optical biosensors for testosterone measurement.

Maryam NikkhahSajedeh KaramiSeyyed Hossein KhatamiMehrnoosh Azimi SanaviAmir SavardashtakiAmir MahmoodzadehZahra ShabaninejadOmid VakiliPegah MousaviFarhad Ghanizadeh GerayeliHamid BehroujHassan GhasemiAhmad Movahedpour
Published in: Biotechnology and applied biochemistry (2022)
Testosterone is an anabolic steroid and a major sex hormone in males. It plays vital roles, including developing the testis, penis, and prostate, increasing muscle and bone, and sperm production. In both men and women, testosterone levels should be in normal ranges. Besides, testosterone and its analogs are major global contributors to doping in sport. Due to the importance of testosterone testing, novel, accurate biosensors have been developed. This review summarizes the various methods for testosterone measurement. Also, recent optical and electrochemical approaches for the detection of testosterone and its analogs have been discussed.
Keyphrases
  • replacement therapy
  • high resolution
  • prostate cancer
  • smoking cessation
  • molecular docking
  • body composition
  • mass spectrometry
  • soft tissue
  • electron transfer
  • solid phase extraction