Gallic acid triphenylphosphonium derivatives TPP+-C10 and TPP+-C12 inhibit mitochondrial function in Candida albicans exerting antifungal and antibiofilm effects.
Victoria ValderramaPaula SánchezMacarena DelsoMario Díaz-DosqueAlejandro EscobarMauricio BudiniMabel CatalánRaúl VivarRodrigo López-MuñozJosé Antonio JaraAlfredo Molina-BerríosPublished in: Journal of applied microbiology (2024)
Derivatives of gallic acid linked to a TPP+ group exert antifungal and antibiofilm activity through impairment of mitochondrial function in C. albicans.