Inflammation is correlated with abnormal functional connectivity in unmedicated bipolar depression: an independent component analysis study of resting-state fMRI.

Guixian TangPan ChenGuanmao ChenShuming ZhongJiaYing GongHui ZhongTao YeFeng ChenJurong WangZhenye LuoZhangzhang QiYanbin JiaYing WangLi Huang

Published in: Psychological medicine (2021)

Our findings that serum IL-8 levels are associated with impaired FC in the right precentral gyrus in BD II patients suggest that inflammation might play a crucial role in brain functional abnormalities in BD.

Keyphrases

resting state
functional connectivity
oxidative stress
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
depressive symptoms
peritoneal dialysis
bipolar disorder
multiple sclerosis
patient reported outcomes
physical activity
subarachnoid hemorrhage
patient reported