Mid-trimester amniotic fluid proteome's association with spontaneous preterm delivery and gestational duration.

Maria HallingströmPetra ZedníkováVojtěch TamborMalin BarmanMarie VajrychováJuraj LenčoFelicia ViklundLinda TancredHardis RabeDaniel JonssonAlisa KachikisStaffan NilssonMarian KacerovskýKristina M Adams WaldorfBo Jacobson
Published in: PloS one (2020)
Neutrophil gelatinase-associated lipocalin and Plasminogen activator inhibitor 1 are potential biomarkers of spontaneous preterm delivery and gestational duration but the findings could not be replicated. The negative findings are supported by the fact that none of the nine proteins from the exploratory phase were significant after correction for multiple testing.