Transcriptome Analysis Reveals Novel Genes Associated with Cartilage Degeneration in Posttraumatic Osteoarthritis Progression.

Chih-Chung LiuHoong-Chien LeeYi-Shian PengAilun Heather TsengJia-Lin WuWei-Yuan TsaiChih Shung WongLi-Jen Su

Published in: Cartilage (2019)

Our study identified 22 novel dysregulated genes and axon guidance pathway associated with articular cartilage degeneration in PTOA progression. These findings provide the potential candidates of biomarkers and therapeutic targets for further investigation.

Keyphrases

rheumatoid arthritis
genome wide
gene expression
extracellular matrix
genome wide identification