Irinotecan and temozolomide chemotherapy in paediatric and adult populations with relapsed Ewing Sarcoma.

S SalahY H ToO KhozouzT IsmailS YaserA AlnsourO ShahinI SultanR AbuhijlihH HalalshehF AbuhijlaJeremy H Lewin

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2020)

Irinotecan and temozolomide (IT) chemotherapy has activity for relapsed ES, with favourable toxicity and equally observed objective responses in the paediatric and adult populations. The observed superior PFS for the paediatric cohort requires further confirmation in future studies.

Keyphrases

intensive care unit
acute lymphoblastic leukemia
emergency department
acute myeloid leukemia
multiple myeloma
diffuse large b cell lymphoma
hodgkin lymphoma
locally advanced
newly diagnosed
oxidative stress
genetic diversity
current status
radiation therapy
rectal cancer