MRI detection of brain gadolinium retention in multiple sclerosis: Magnetization transfer vs. T1-weighted imaging.
Carmen CananauYngve ForslinÅsa BergendalHenrik SjöströmKatharina FinkRussell A OuelletteMaria Kristoffersen WibergSten FredriksonTobias GranbergPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2023)
Conventional T1-weighted imaging provided dose-dependent associations with gadolinium administrations in MS, while these could not be detected with 2-dimensional MT. Future studies could explore newer MT techniques like 3D and inhomogenous MT. Notably, these associations were identified with conventional MRI even though most patients had not received gadolinium administrations in the preceding 9 years, suggestive of long-term retention.
Keyphrases
- contrast enhanced
- multiple sclerosis
- magnetic resonance imaging
- magnetic resonance
- computed tomography
- high resolution
- diffusion weighted imaging
- end stage renal disease
- white matter
- ejection fraction
- chronic kidney disease
- newly diagnosed
- mass spectrometry
- peritoneal dialysis
- ms ms
- patient reported outcomes
- subarachnoid hemorrhage
- real time pcr
- loop mediated isothermal amplification