Short-term and Long-term Outcomes of a Disruption and Disconnection of the Pancreatic Duct in Necrotizing Pancreatitis: A Multicenter Cohort Study in 896 Patients.
Hester C TimmerhuisSven M van DijkRobbert A HollemansChristina J Sperna WeilandDevica S UmansLotte BoxhoornNora H HallenslebenRogier van der SluijsLieke BrouwerPeter van DuijvendijkLiesbeth KagerSjoerd KuikenJan-Werner PoleyRogier de RidderTessa E H RömkensRutger QuispelMatthijs P SchwartzAdriaan C I T L TanNiels G VennemanFrank P VleggaarRoy L J van WanrooijBen J WittemanErwin J van GeenenI Quintus MolenaarMarco J BrunoJeanin E van HooftMarc G BesselinkRogier P VoermansThomas L BollenRobert C VerdonkHjalmar C van Santvoortnull nullPublished in: The American journal of gastroenterology (2023)
At least 1 of every 4 patients with necrotizing pancreatitis experience DPD, which is associated with detrimental, short-term and long-term interventions, and complications. Central and subtotal pancreatic necrosis and high levels of serum C-reactive protein in the first 48 hours are independent predictors for DPD.